Prostate Cancer in Dogs​

Prostate cancer is a rare but serious condition that can affect male dogs, especially as they age. Like humans, dogs have a prostate gland, which plays an essential role in reproductive health. Understanding the symptoms, diagnosis, treatment options, and prognosis for prostate cancer in dogs is crucial for pet owners to make informed decisions about their dog’s care.

Do Dogs Have Prostates?

Yes, dogs do have prostates. The prostate gland is located near the neck of the bladder, surrounding the urethra, and is responsible for producing a fluid that helps transport sperm during ejaculation. In intact (non-neutered) male dogs, the prostate is a vital component of the reproductive system. Even after neutering, the prostate remains, though it typically shrinks in size.

Key Functions of the Prostate in Dogs:

1. Producing seminal fluid to aid sperm motility.
2. Protecting sperm from the acidic environment of the female reproductive tract.

While benign enlargement (benign prostatic hyperplasia or BPH) is common in older, intact dogs, prostate cancer is a more aggressive and less common condition.

Do Dogs Get Prostate Cancer?

Yes, dogs can get prostate cancer, though it is relatively rare. Unlike BPH, which primarily affects intact dogs, prostate cancer can occur in both neutered and intact dogs. In fact, neutered dogs may have a slightly higher risk due to hormonal changes after neutering.

Prostate cancer in dogs is usually adenocarcinoma, a highly malignant tumor that tends to spread (metastasize) rapidly to other organs, including the lungs, bones, and lymph nodes.

What Causes Prostate Cancer in Dogs?

The exact cause of prostate cancer in dogs is not fully understood, but several factors may contribute:

• Hormonal Changes: Imbalances in sex hormones, especially after neutering, may increase the risk.
• Genetics: Certain breeds, such as Doberman Pinschers, Shetland Sheepdogs, and Scottish Terriers, may be predisposed.
• Age: Older dogs (usually over 9 years) are more commonly affected.
• Environmental Factors: Exposure to environmental toxins, chemicals, or carcinogens may play a role.

Dog Prostate Cancer Symptoms

Prostate cancer symptoms in dogs are often subtle in the early stages but become more pronounced as the disease progresses. Common signs include:

Early-Stage Symptoms:

1. Difficulty urinating: Straining to urinate or frequent attempts with little output.
2. Blood in urine: Hematuria is a common early symptom.
3. Changes in defecation: Constipation or straining due to an enlarged prostate pressing on the rectum.
4. Frequent urination: Increased frequency or urgency.

Advanced Symptoms:

1. Lameness or difficulty walking: Pain in the rear limbs or stiffness due to metastasis to the bones.
2. Weight loss and lethargy: A general decline in energy and appetite.
3. Pain or discomfort: Abdominal pain, especially near the lower back or pelvic area.
4. Loss of bladder control: Incontinence or dribbling urine.

If any of these symptoms are observed, immediate veterinary attention is crucial for diagnosis and treatment.

Dog Prostate Cancer End Stage: What to Expect

In the end stage of prostate cancer, dogs may experience a rapid decline in health. Common signs include:

• Severe weight loss and muscle wasting
• Persistent pain, especially in the pelvic region
• Difficulty standing or walking
• Inability to control urination or defecation
• Labored breathing if cancer has spread to the lungs

End-stage prostate cancer is often accompanied by significant discomfort, making pain management a primary focus.

Dog Prostate Cancer: When to Euthanize

Deciding when to euthanize a dog with prostate cancer is a deeply personal and difficult decision. The primary consideration should be the dog’s quality of life. Factors to consider include:

• Unmanageable pain: If pain cannot be controlled even with medication.
• Loss of mobility: Inability to stand, walk, or move without assistance.
• Loss of appetite: Persistent refusal to eat, leading to severe weight loss.
• Incontinence: Inability to control urination or defecation, causing distress.
• Difficulty breathing: Indicating potential metastasis to the lungs.

Consulting with a veterinarian can help determine when euthanasia may be the most compassionate choice.

Treatment for Dog Prostate Cancer

Treatment for prostate cancer in dogs focuses on managing symptoms, slowing disease progression, and improving the dog's quality of life. Prostate cancer in dogs is often aggressive, making complete remission difficult, but early intervention can offer better outcomes.

Here are the common treatment options:

1. Surgical Intervention

In some cases, surgery may be an option, though it is rarely curative due to the aggressive nature of prostate cancer.

• Prostatectomy (Partial or Total): Removal of part or all of the prostate gland. This is rarely performed because it carries high risks, including urinary incontinence.
• Biopsy: May be used to confirm the diagnosis but not always recommended as a treatment option.

2. Chemotherapy

Chemotherapy is often used to slow the spread of prostate cancer and reduce tumor size.

• Drugs Used: Carboplatin, doxorubicin, or mitoxantrone are commonly used chemotherapy agents.
• Goal: Extend life expectancy and reduce symptoms, not typically curative.

3. Radiation Therapy

Radiation can help shrink the tumor and alleviate pain or other symptoms caused by the tumor pressing on surrounding tissues.

• External Beam Radiation: Targets the prostate gland to shrink tumors and reduce pain.
• Side Effects: May include localized hair loss, irritation, or gastrointestinal upset.

4. Palliative Care

Palliative care focuses on improving the dog’s quality of life when curative treatment is not possible.

• Pain Management: Non-steroidal anti-inflammatory drugs (NSAIDs) like piroxicam or meloxicam can reduce inflammation and discomfort.
• Bladder Support: Medications to manage urinary incontinence or difficulty urinating.
• Nutritional Support: Specialized diets to maintain strength and weight.

5. Hormonal Therapy

Since canine prostate cancer does not always respond to hormones like human prostate cancer, hormonal therapies such as castration or anti-androgens are less commonly used but may still be considered in some cases.

6. Experimental Treatments

In some cases, clinical trials may offer access to new therapies that are not yet widely available. These can include novel drugs or advanced radiation techniques.

Dog Prostate Cancer Life Expectancy

Prostate cancer in dogs is aggressive, and prognosis is generally poor. Life expectancy after diagnosis varies based on factors like the stage of cancer, the dog’s overall health, and treatment options chosen.

• Without treatment: Life expectancy is typically 1 to 3 months.
• With treatment (chemotherapy, radiation): Life expectancy may extend to 6 to 12 months, but the quality of life remains a critical concern.

Conclusion

Prostate cancer in dogs is a challenging condition, both for dogs and their owners. While it is relatively rare, it is highly aggressive and often presents late in the disease process. Recognizing early symptoms, seeking timely veterinary care, and understanding treatment options are essential for managing this disease. Ultimately, the focus should be on maintaining the dog’s quality of life, and euthanasia may be a compassionate choice when suffering becomes unmanageable.

FAQs 

1. Can neutered dogs get prostate cancer?

Yes, neutered dogs can get prostate cancer, and they may even have a slightly higher risk due to hormonal imbalances post-neutering.

2. Is prostate cancer in dogs curable?

Prostate cancer in dogs is not curable. Treatment focuses on managing symptoms and improving quality of life.

3. How is prostate cancer in dogs diagnosed?

Diagnosis involves a combination of physical exams, blood tests, ultrasound imaging, and sometimes biopsy of the prostate tissue.

4. What are the treatment options for prostate cancer in dogs?

Treatment may include chemotherapy, radiation therapy, pain management, and supportive care. Surgery is rarely an option due to the invasive nature of the cancer.

5. Can diet affect prostate cancer in dogs?

While no specific diet can cure prostate cancer, a high-quality, balanced diet can support overall health. Some vets may recommend diets rich in antioxidants to support immune function.