Back To TOP
Back To TOP

Anti-Inflammatory Supplements for Cats: Treating And Preventing Hot Spots

icon Last Updated August 15, 2025

Hot spots—also known as acute moist dermatitis—are painful, inflamed areas of skin that can appear suddenly on cats. While often associated with dogs, cats can also develop these raw, irritated patches due to allergies, insect bites, overgrooming, or skin infections.

If left untreated, hot spots can spread rapidly, causing significant discomfort for your feline friend. Beyond immediate treatment, anti-inflammatory supplements can play a vital role in reducing skin irritation, supporting immune function, and preventing future flare-ups.

In this guide, you’ll learn:

  • What causes hot spots in cats

  • How anti-inflammatory supplements help treat and prevent them

  • The best natural and veterinary-approved supplements for cats

  • Dosage considerations and safety tips

  • Prevention strategies for long-term skin health

What Are Hot Spots?

A hot spot is a localized area of inflamed, infected skin. It often appears as a red, moist, hairless patch that may ooze fluid. Hot spots are usually itchy and painful, leading cats to lick, scratch, or bite the area—making the condition worse.

Common symptoms include:

  • Redness and swelling

  • Scabs or crusting

  • Hair loss in the affected area

  • Warm skin to the touch

  • Oozing or foul odor

  • Excessive grooming of the spot

    excessive grooming cats

Causes of Hot Spots in Cats

Hot spots can develop from many triggers, including:

  1. Allergies

    • Food allergies (e.g., chicken, beef, grains)

    • Environmental allergies (dust, pollen, mold)

    • Flea allergy dermatitis

  2. Parasites

    • Fleas, mites, or ticks

  3. Skin Trauma

    • Scratches or bites that become infected

  4. Underlying Skin Conditions

    • Fungal or bacterial infections
      fungal infection in cats

    • Atopic dermatitis

  5. Stress or Behavioral Overgrooming

    • Anxiety can lead to obsessive licking and chewing

Why Anti-Inflammatory Support Matters in Hot Spot Treatment & Prevention

Hot spots are not only a surface problem—they are a sign of inflammation in the skin and sometimes the whole immune system. Addressing inflammation internally can:

  • Reduce itching and redness

  • Support faster healing

  • Prevent recurrence

  • Strengthen skin barrier function

This is where anti-inflammatory supplements for cats can help.

How Anti-Inflammatory Supplements Work in Cats

1. Targeting the Root Cause of Inflammation

Inflammation is part of the body’s immune response, but when it’s excessive or chronic, it can damage tissues. Supplements can:

  • Reduce inflammatory chemicals like prostaglandins and cytokines

  • Support healthy immune regulation

  • Improve skin hydration and elasticity

2. Key Benefits for Cats with Hot Spots

  • Faster Recovery: By calming the inflammatory response, wounds heal quicker.

  • Less Itching: Natural compounds can soothe irritated nerve endings.

  • Stronger Skin Barrier: Nutrients like omega-3s help keep skin resilient.

  • Reduced Risk of Future Flare-Ups: Ongoing supplementation can lower recurrence rates.

Best Anti-Inflammatory Supplements for Cats

1. Omega-3 Fatty Acids (Fish Oil)

Source: Salmon oil, krill oil, anchovy oil

  • How it works: Omega-3s (EPA and DHA) reduce the production of inflammatory molecules.

  • Benefits: Improves skin moisture, reduces redness, supports joint health.

  • Dosage: Typically 20–30 mg EPA+DHA per pound of body weight (consult your vet).

  • Safety tips: Choose pet-specific fish oil; store in the fridge to prevent oxidation.

    Anti-Inflammatory Supplements for Cats: Treating & Preventing Hot Spots

2. Omega-6 Fatty Acids (in Balance with Omega-3s)

Source: Evening primrose oil, borage oil

  • How it works: Supports skin structure and barrier function.

  • Note: Too much omega-6 can worsen inflammation—balance is key.

3. Turmeric (Curcumin)

How it works: Contains curcumin, a potent anti-inflammatory and antioxidant.

  • Benefits: Reduces skin swelling, promotes wound healing.

  • Form: Pet-safe turmeric supplements or curcumin capsules with bioavailability enhancers.

  • Caution: Must be dosed carefully; raw turmeric powder is not well absorbed.

4. Quercetin

Nicknamed: “Nature’s Benadryl”

  • How it works: Natural plant flavonoid that reduces histamine release.

  • Benefits: Calms allergic reactions, reduces redness and swelling.

  • Form: Often combined with bromelain for better absorption.

5. Probiotics

How it works: Supports gut health, which influences immune function and skin health.

  • Benefits: Reduces allergy-related inflammation, supports nutrient absorption.

6. Vitamin E

  • How it works: Antioxidant that protects skin cells from oxidative stress.

  • Benefits: Moisturizes skin, reduces scarring.

  • Usage: Can be given orally or applied topically to certain wounds (with vet guidance).

7. CBD Oil (Hemp-Derived, THC-Free)

  • How it works: Modulates inflammatory pathways via the endocannabinoid system.

  • Benefits: Pain relief, reduced itching, stress reduction.

  • Caution: Use only cat-specific formulas free of THC.

8. Green-Lipped Mussel

  • How it works: Rich in omega-3s, antioxidants, and anti-inflammatory compounds.

  • Benefits: Supports skin, joint, and immune health.

Choosing the Right Supplement for Your Cat

Factors to Consider

  • Underlying cause of hot spots (allergy, parasite, infection)

  • Cat’s age and weight

  • Other health conditions (kidney, liver issues)

  • Form preference: Liquid, powder, chewable, capsule

Working with Your Veterinarian

Never start supplements without vet approval—some natural compounds can interact with medications or cause side effects.

How to Give Supplements to Cats Without a Fight

Cats are notoriously picky. Here are proven tips:

  • Mix into wet food (use strong-smelling flavors like tuna)

  • Use pill pockets for capsules

  • Choose flavored liquid supplements

  • Start with tiny amounts and increase gradually

Prevention: Reducing Hot Spot Risk Long-Term

Maintain Flea and Parasite Control

  • Year-round flea prevention is essential.

    Protect your pets with the Puainta® Pest Control Collar! Safely repelling ticks and fleas, it also reduces anxiety, promotes emotional balance, and eases stress-related behaviors—all with pet-safe Margosa extract and comfortable elastic protection.

    flea control collar

Balanced Diet

  • Choose high-quality cat food with adequate protein and omega fatty acids.

Grooming Routine

  • Brush regularly to remove loose fur and check for skin problems.

Reduce Stress

  • Provide enrichment (scratching posts, toys, climbing shelves)

  • Use pheromone diffusers for anxious cats

Manage Allergies

  • Identify and remove allergens from the environment or diet.

Possible Side Effects and Safety Concerns

Even natural supplements can cause issues:

  • Diarrhea or vomiting (if dosage is too high)

  • Allergic reactions to certain ingredients

  • Interactions with medications (especially blood thinners)

Always introduce supplements gradually and monitor your cat.

Step-by-Step Treatment Plan for Cats with Hot Spots

  1. Identify and treat the cause (fleas, allergy, wound)

  2. Clean the area (vet-recommended antiseptic)

  3. Apply topical treatment if prescribed

    Soothe your pet’s itchy, irritated skin fast with Puainta® Quantum Silver Anti-Itch Spray! Safe for dogs and cats, it helps heal hot spots, fight fungal and bacterial infections, and provides instant relief without stinging—leaving your furry friend comfortable and happy!

    hot spots skin spray itchy relief for cats

  4. Introduce anti-inflammatory supplements for healing support (after consulting the vet)

  5. Monitor daily for improvement

  6. Prevent recurrence with ongoing care and supplementation

Final Thoughts

Anti-inflammatory supplements are not a magic cure—but when paired with proper veterinary care, they can speed recovery, reduce discomfort, and prevent future hot spots in cats. By targeting inflammation at its source, you help your cat heal from the inside out.

FAQ: 

Q1: Can I give my cat human anti-inflammatory supplements?
Not without veterinary approval—dosages and formulations for humans may be unsafe for cats.

Q2: How long does it take for supplements to work?
It varies—omega-3s may take 4–6 weeks, while quercetin or CBD may help within days.

Q3: Are supplements enough to cure hot spots?
No—supplements should be part of a complete treatment plan including vet care, topical treatment, and parasite control.

Q4: Can kittens take anti-inflammatory supplements?
Some supplements are safe for kittens, but always consult your vet first.

Q5: What’s the best supplement for preventing hot spots?
Omega-3 fatty acids are widely recommended for skin health and inflammation control.

Dr.Emily Carter,DVM
Dr. Emily Carter is a dedicated veterinarian with over 15 years of experience in small animal medicine. She graduated from the University of California, Davis, one of the top veterinary schools in the country, where she earned her Doctor of Veterinary Medicine (DVM) degree.
View all posts by Dr.Emily Carter,DVM

Join The Puainta

Become one of pet parents and get professional tips, immediate product info, updated promotions and discounts, and more surprises from us!

puainta